Physical dependence over a prescribed medication isn't going to signify addiction. Actual physical dependence involves the prevalence of a withdrawal syndrome when There's unexpected reduction or cessation in drug use or if an opiate antagonist is administered. Physical dependence is often detected right after a couple of days of opioid therapy. No

Early symptoms subsequent a potentially hepatotoxic overdose may perhaps involve: nausea, vomiting, diaphoresis, and standard malaise. Scientific and laboratory evidence of hepatic toxicity will not be obvious until finally forty eight to seventy two hours post-ingestion.Other adverse reactions acquired from postmarketing encounters with PERCOCET t